(11月19日)讲座:A Nanocavity Biochemical Sensor with …
来源:先进材料与纳米生物医学研究院
时间:2009-11-12 浏览:
讲 座:A Nanocavity Biochemical Sensor with Single Molecule Sensitivity
主讲人: Michael J. Naughton( 美国波士顿大学教授、物理系主任)
时 间: 11月19日(星期四)上午10:00
地 点: 同济大学南校区实训楼二楼纳米院会议室
主 办:先进材料与纳米生物医学研究院
演讲者简介:
Mike Naughton the Evelyn J. and Robert A. Ferris Professor
of Physics and Chairman of the Department of Physics at Boston
College. He holds a B.S. in Physics from St. John Fisher College
in Rochester, NY and a Ph.D. from Boston University. Prior to
joining BC in 1998, he was for ten years a faculty member in the
Physics Department at the State University of New York at Buffalo.
He is a Fellow of the American Physical Society, winner of the NSF
Young Investigator Award and a former member of the Executive
Committee of the APS Division of Condensed Matter Physics. He also
spent one year as BC Associate Vice President for Research.
Naughton’s research has concentrated on experimental condensed
matter & materials physics and integrated science, which resides
at the interface of physics, chemistry, biology, engineering and
medicine. He has published more than 150 scientific papers, and
holds more than 20 patents. His particular research interests are in
low dimensional electron physics, the manipulation of light on the
nanoscale, and nanobiodetection. His present research projects
include organic superconductivity, high efficiency solar power,
development of a nanostructured retinal implant, and cancer detection
using nanotechnology. Naughton has cofounded two technology companies,
the most recent of which is Solasta Inc. (Newton, Mass.),
a venture-backed solar energy company that is developing
nanotechnology-based high efficiency, low cost solar cells,
based on BC inventions. Naughton is CTO at Solasta.
演讲摘要:
We discuss a novel nanoscale platform for biological and chemical sensing with
potential for multiplexed detection of pathogens, viruses, cancer biomarkers, etc. The "nanocavity" sensor is capable of detecting small changes in complex
impedance resulting from the presence of target molecules in and near the device. Its nanoscale dimensions can be tuned for size-specificity, and its constituent
components functionalized for biochemical specificity. Target molecules
entering the coax annuli in the sensor array (one million sensors per square
millimeter) are shown to result in a significant change in complex
impedance as a function of time, frequency and concentration, with a detection
sensitivity of ~1 molecule per nanocavity.